Through the ATT&CK framework, MITRE has generated a gold mine of information about the most important tactics and techniques used by attackers and how the blue team can detect and prevent these actions.
Blocking atomic attack indicators such as domain names and IP addresses might work in the short term, but understanding the higher-level tactics in ATT&CK helps the blue team identify and anticipate attacker activity at a higher level of abstraction.
In this white paper, SANS author and dedicated blue team member John Hubbard explores how ATT&CK slows attackers down and gives defenders a fighting chance.